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Luvox (Fluvoxamine)

Luvox, which is the brand name of the drug called fluvoxamine, is part of a class of antidepressants called selective serotonin-reuptake inhibitors (SSRIs) and is used to treat obsessive compulsive disorder (OCD) and anxiety.


Luvox is available by prescription only and comes in a tablet or a slow-release capsule. The capsule form is taken once a day, usually at bedtime, while the tablet form is taken once or twice each day. It may take several weeks to feel the full effects of this medication. A person's doctor may slowly increase the amount of the drug taken each day to find the correct dose.

Important Information Before Use

Talk to your doctor before you take Luvox if you have or have ever had seizures or any type of liver, adrenal, kidney, or heart disease. Let your doctor know if you take or have taken street drugs or if you use alcohol frequently; these substances can interfere with this medication. You should also mention any serious reactions you have had to other similar medications.


Luvox may interact with other medications or supplements, including MAO inhibitors, aspirin, nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin) and naproxen (Aleve), migraine medications, anticoagulants, antihistamines, antidepressants, antacids, medications for anxiety, St. John's Wort, sleeping pills, antipsychotics, high blood pressure medications, and more. If you are taking any other prescription drugs or vitamins, you should check with your doctor or pharmacist before taking Luvox. Do not take this medication within two weeks of taking a monoamine oxidase (MAO) inhibitor; you should let your doctor know if you have taken an MAO inhibitor recently.

Important Information During Use

  • You should talk to your doctor about alternative treatments for depression if you are pregnant or become pregnant while taking Luvox. This drug can cause problems in newborns if taken during pregnancy or while breastfeeding.
  • Avoid driving or working with heavy machinery until you know how your prescription affects you; this medication can make you very drowsy. Using alcohol can worsen this side effect.
  • Cigarettes and tobacco use may interfere with the effectiveness of this medication.
  • If you are having any type of surgery, including oral or dental surgery, then you should tell your doctor or anesthesiologist that you take this medication.
  • You should not take more than the amount of medication prescribed by your doctor. It is possible to take too much of this medication. Signs of overdose include lowered potassium levels, low blood pressure, rapid heart rate, breathing problems, drowsiness, and vomiting.

Side Effects

Antidepressants including Luvox may cause an increase in suicidal thoughts or behavior in children, teens, or young adults under twenty-four years old. Your doctor can help you decide if the benefit of this medication outweighs the risk of using it. Call your doctor right away if you experience serious or severe side effects from taking this medication. Serious side effects may include:

  • Irregular, pounding, or fast heartbeat
  • Vomiting blood or a substance that looks like coffee grounds
  • Bloody or black stools
  • Dizziness or loss of consciousness
  • Fever
  • Seizures
  • Muscle stiffness
  • Hallucinations
  • Chest pain
  • Dizziness
  • Rash or hives
  • Uncontrollable shaking
  • Difficult or slow breathing
  • Numbness, pain, or tingling in extremities
  • Nosebleeds

Less serious side effects of this drug may include:

  • Difficulty with memory or concentration
  • Drowsiness, weakness, or unsteadiness
  • Dry mouth
  • Nausea, stomach pain, gas, vomiting, diarrhea, or constipation
  • Changes in sex drive or ability
  • Headache
  • Decrease in appetite, weight loss


If you need to stop taking this medication, your doctor will work with you to slowly reduce the amount of Luvox you take over time. Tapering slowly off of this medication will help reduce the severity and the number of side effects that you experience. Symptoms of withdrawal may include:

  • Agitation
  • Irritability
  • Dizziness
  • Anxiety
  • Headache
  • Confusion
  • Burning or tingling sensation

Talk with your doctor if you experience any withdrawal symptoms.



  1. Highlights of prescribing information. (2014, July). Retrieved from http://luvoxcr.com/LuvoxCR_PI_Rev0714_Clean.pdf
  2. Luvox® (fluvoxamine). (2013, January). Retrieved from http://www.nami.org/Content/ContentGroups/Helpline1/Luvox_%28fluvoxamine%29.htm

Page content reviewed by James Pendleton, ND


Last Update: 12-16-2014


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