Researchers Discover Common Cause of Dementia

An elderly couple sits on a park benchOne in three seniors dies with symptoms of Alzheimer’s or another form of dementia, yet this memory-stealing group of diseases is still not well-understood. Researchers at the Krembil Neuroscience Centre say they’ve uncovered a major cause of dementia, though, and have published their results in Annals of Neurology. 

White Matter Damage and Dementia

Seniors frequently experience some damage to their brains’ white matter, and the damage is usually harmless. But previous research suggests that people with extensive white matter damage are more likely to experience symptoms of memory loss or cognitive impairment. Prior to this study, doctors were unsure what caused white matter damage in seniors, with most speculating that it’s just part of the normal aging process.

This study’s authors theorized that white matter degeneration might actually be the product of tiny strokes. To evaluate this hypothesis, researchers studied five people with white matter degeneration, conducting detailed MRI brain scans every week for 16 weeks. During the study, researchers noticed small white spots appearing on participants’ brains. The spots were characteristic of small strokes. While these spots initially appeared not to yield any symptoms, they ultimately began looking like the existing damaged white matter spots in the participants’ brains. This suggests that tiny strokes are more common than suspected and that, over time, the damage caused by these spots can lead to white matter deterioration.

The study’s authors point to the need for a larger study sample to verify their findings. If small strokes really are a major cause of dementia, though, this could provide new treatment and prevention options for dementia.

The Psychology of a Dementia Diagnosis

Though new research offers hope for people suffering from dementia as well as those at risk of developing the condition in the future, not everyone wants to undergo testing for the disease. Lillian Rozin, a Topic Expert on aging and geriatric concerns, says that many seniors mistakenly believe that there’s no effective way to treat the disorder. “With the advances in understanding the causes and factors in the development of dementia, people and their caregivers will have more options for medical treatment and early intervention,” she says.

Rozin further emphasizes the role that proper planning and a strong support system can play in treating dementia. “They will also have more options in their holistic care plans. Knowing that you suffer from dementia can help you set up a safe physical environment and arrange for appropriate powers of attorney, etcetera, as you go forward. For many, though, just accepting this diagnosis feels like a huge loss of control and independence, so it can become a battle for dementia patients and their team of family and caregivers. If there will be clearer markers for diagnosing dementia, it will help people to change their lives accordingly and hopefully provide themselves with a better quality of life. But the emotional challenges of having dementia are great for the patient and all those who interact with him day to day. Having a strong support system will help greatly when dealing with this diagnosis,” she explains.


  1. Latest facts & figures report. (2014). Retrieved from
  2. Researchers discover possible cause of common dementia, opening avenues for treatment. (2014, October 30). Retrieved from

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  • Rosalyn

    November 10th, 2014 at 8:25 PM

    Dementia affects not just the diagnosed person but those around him or her too.Its very disheartening to see the suffering of a family with someone with dementia.I don’t know a lot about what exactly the tiny strokes mean,but if there is a more clear cut way of diagnosing this disorder then that could really help the family of the affected person.

  • Sadie

    November 11th, 2014 at 3:48 AM

    Great news for a change! Dementia takes away so much from so many vibrant lives, it would be wonderful if this finding could help move the research forward.

  • keith

    November 11th, 2014 at 10:47 AM

    This is another clue to dementia and the causes but also another indicator of just how closely physical and mental health issues are both tied together. Perhaps we could begin to stress more the importance of keeping blood pressure numbers lower so that this could potentially reduce the number of these types of strokes that people are having.

  • Hank

    November 13th, 2014 at 3:47 AM

    This would have to be a terrible diagnosis to receive, not only for the patient but for the entire family.
    It will be hard watching someone that you love who has always been so vibrant progress into this space where they no longer know anyone and have a difficult time remembering anything.
    I do hope that one day in the very near future there are some ways that are developed to at least slow the progression, because I have to say this for me would have to be one of the most terrible ones to watch progress and take away a life.

  • Lucas

    November 17th, 2014 at 10:43 AM

    I know that no one ever wants to hear the words that this is what they are facing, but I would much rather know the truth and elan it early on instead of waiting until it has become very advanced before getting any sort of answers.

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