Can Antidepressants Stop Working?

Can antidepressants stop working?

Infographic Text: Can Antidepressants Stop Working?

Yes. Some people do develop a tolerance to antidepressants, seeing less and less results from a drug that previously helped. This process is sometimes called ADT tachyphylaxis.

Estimates vary, but research suggests 25% of people taking antidepressants for depression will eventually develop a tolerance. This number rises to 42% for people diagnosed with dysthymia, a type of long-lasting depression.

People experiencing antidepressant tolerance have several options. They can seek a clinical evaluation to make sure they have depression and not bipolar. They can ask their psychiatrist to help them switch to a new medication. They may also seek out additional treatments such as psychotherapy.

References:

  1. Antidepressant dependency and withdrawal [PDF]. (2018). All-Party Parliamentary Group for Prescribed Drug Dependence. Retrieved from https://bit.ly/2FsMQrV
  2. Hall-Flavin, D. K. (2018, Jan 31). Antidepressants: Can they stop working? Retrieved from https://mayocl.in/2H3GkKg

© Copyright 2019 GoodTherapy.org. All rights reserved.

The preceding article was solely written by the author named above. Any views and opinions expressed are not necessarily shared by GoodTherapy.org. Questions or concerns about the preceding article can be directed to the author or posted as a comment below.

Leave a Comment

By commenting you acknowledge acceptance of GoodTherapy.org's Terms and Conditions of Use.

* Indicates required field.

GoodTherapy uses cookies to personalize content and ads to provide better services for our users and to analyze our traffic. By continuing to use this site you consent to our cookies.