Bipolar Genetic Map May Lead to Prevention and Better Treatments
December 1st, 2008 |A GoodTherapy.org News Update Presented by Jolyn Wells-Moran, PhD, MSW
What if we were able to identify who is at risk for development of bipolar disorder even before it occurs? What if we were then able to prevent the illness from ever occurring in those lives? What if we could individualize treatment for bipolar disorder according to the precise genes contributing to the person’s disorder? It now appears that with genetic testing, prevention and better treatment may be attainable in the foreseeable future, thanks to a major study funded by the National Institute of Mental Health.
The group of neuroscientists initially gleaned data from genome-wide association research and other results on the activity of genes in humans and animals. Alexander B. Niculescu III, M.D., Ph.D., Indiana University, said, “The process was similar to a Google approach, the more links there are to a page on the Internet, the more likely it is to come up at the top of your search list.” In other words, they looked at genes that had already been identified as contributing to bipolar disorder, in the existing research literature, and prioritized them on the strength of evidence. The investigators were then able to create a genetic map of the disorder, a landmark development. Read the rest of this entry »
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