Prozac (fluoxetine) is part of a group of relatively newer antidepressant medications called selective serotonin reuptake inhibitors (SSRIs). This prescription medication effectively increases the amount of serotonin—a neurotransmitter related to mood—in the body. Newer antidepressant medications like Prozac were developed to produce fewer side effects than older antidepressant medications such as monoamine oxidase inhibitors (MAOIs), tricyclics, and tetracyclics.

Mental Health Conditions Treated with Prozac

This medication is chiefly used to treat depression in adults, teenagers, and children. It may also be prescribed for the treatment of obsessive compulsive thoughts and behaviors in adults and children, bulimia nervosa in adults, panic attacks in adults, treatment-resistant depression in adults, and adults with depressive episodes associated with bipolar I. Prozac may help to control the behavior, emotions, and thoughts that sometimes accompany these conditions, but it is not intended to cure the diagnosis.

FAQs

Warnings Before Use

This medication may lead to or increase suicidal thoughts and actions in young adults (aged 24 or younger), teenagers, and children—especially at the start of treatment or if the dosage is altered. In addition to acts and thoughts of suicide, one study suggests that this drug may increase self-harm, aggression, and violence in children and adolescents. Pay attention to new or sudden changes in mood, thoughts, or behavior. Contact your health care provider if any changes appear severe, or if they concern you.

People who use this drug may develop a potentially life-threatening condition called serotonin syndrome. This condition is characterized by high or low blood pressure, racing heartbeat, muscle stiffness, muscle twitching, dizziness, diarrhea, nausea, vomiting, tremors, seizures, and loss of consciousness.

If you have ever had a heart attack, a history of heart disease, diabetes, glaucoma, or liver disease, talk to your health care provider before you take Prozac. Talk to your doctor about any electroshock therapy you are receiving or have received prior to beginning this medication. Adults over the age of 65 may experience severe side effects; if you are in this age group, work with your doctor to find an alternative treatment for your condition.

It is possible for this drug to interact with other medications or supplements, including antihistamines, anticoagulants, other antidepressants, antifungals, medication for sleep issues, herbal supplements, pain relief medication, blood pressure drugs, migraine medications, vitamins, minerals, and more. If you are taking any prescription drugs or regularly taking supplements, ask your doctor about any possible interactions before taking Prozac.

Important Information During Use

Prozac, like many SSRIs, carries significant risks of which to be aware. If you are prescribed this medication, talk to your doctor and pharmacist about the following:

Possible Side Effects

If you experience side effects from this medication, you should inform your doctor or psychiatrist right away. Serious side effects may include:

Less serious side effects may include:

How to Safely Withdraw

Work out a plan with your doctor before reducing or stopping this medication; you should not stop taking it abruptly. You may reduce the intensity of withdrawal symptoms by tapering off of this medication over time. Possible symptoms of withdrawal include:

References:

  1. Citizens Commission on Human Rights International. (2012). The side effects of common psychiatric drugs. Retrieved from http://www.cchrint.org/pdfs/The_Side_Effects_of_Common_Psychiatric_Drugs.pdf
  2. Drugs.com. (2014). Prozac. Retrieved from http://www.drugs.com/prozac.html
  3. Medline Plus. (2014). Fluoxetine. Retrieved from http://www.nlm.nih.gov/medlineplus/druginfo/meds/a689006.html
  4. RxList. (2014). Prozac. Retrieved from http://www.rxlist.com/prozac-drug.htm
  5. United States Food and Drug Administration. (2009). Medication guide: Prozac. Retrieved from http://www.fda.gov/downloads/drugs/drugsafety/ucm088999.pdf.

Page content reviewed by James Pendleton, ND